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・ Spirotropis ephamilla
・ Spirotropis eurytima
・ Spirotropis genilda
・ Spirotropis gramensis
・ Spirotropis laodice
・ Spirotropis limula
・ Spirotropis lithocolleta
・ Spirotropis modiolus
・ Spirotropis monterosatoi
・ Spirotropis patagonica
・ Spirotropis phaeacra
・ Spirotropis remota
・ Spirotropis stirophora
・ Spirotropis studeriana
・ Spirotropis tmeta
Spirotryprostatin A
・ Spirotryprostatin B
・ Spirou
・ Spirou (comics)
・ Spirou (magazine)
・ Spirou (video game)
・ Spirou Charleroi
・ Spirou et Fantasio
・ Spirou et Fantasio (comic book)
・ Spirou et Fantasio (TV series)
・ Spirou et l'aventure
・ Spirou et les hommes-bulles
・ Spirou et les héritiers
・ Spirou à Moscou
・ Spirou à New York


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Spirotryprostatin A : ウィキペディア英語版
Spirotryprostatin A

Spirotryprostatin A is an indolic alkaloid from the 2,5-Diketopiperazine class of natural products found in the ''Aspergillus fumigatus'' fungus. Spirotryprostatin A and several other indolic alkaloids (including Spirotryprostatin B, as well as other tryprostatins and cyclotryprostatins) have been found to have anti-mitotic properties, and as such they have become of great interest as anti-cancer drugs. Because of this, the total syntheses of these compounds is a major pursuit of organic chemists, and a number of different syntheses have been published in the chemical literature.
One such total synthesis was published in 1999, which showed that the isopropylidene side chain was not necessary to the biological activity of the compound, leading to a number of new theorized analogues.
== References ==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Spirotryprostatin A」の詳細全文を読む



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